CXXXV.—α-Hydroxyhippuric acid and a new test for hippuric acid

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Colorimetric method for hippuric acid.

FTIPPURIC ACID 1S an important metabolic product normally present in urine in amounts determined by tile ingestion of benzyl-containing foods and medicinals (ii). Because this compound is comparatively inert chemically, identification requires isolation and the determination of physical constants after extensive purification. There has long been need for a reliable and sensitive color reaction ...

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Urinary hippuric acid and orthocresol excretion in

ABSTRACr It is not known whether urinary excretion of hippuric acid (HA) or orthocresol (0-Cr) is to be preferred for the biological monitoring of workers with occupational exposure to toluene. To study this, 42 printing trade workers with more than 10 years' exposure to a mixture of organic solvents including toluene (0-20 ppm) and 43 control subjects matched by age, smoking habits, and living...

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The excretion of m-hydroxyhippuric acid by humans.

The chromatographic behavior of several simple phenolic acids was described recently, and a description of the phenolic acids present in human urine has been given (2). Experiments aimed towards establishing a preliminary identification of many of the urinary acids revealed that several compounds having the characteristics of m-hydroxyphenyl acids are found. These include m-hydroxyhippuric, -be...

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Urinary hippuric acid excretion in everyday life.

The biological monitoring for exposure to toluene is based on the measurement of urinary hippuric acid concentration (HA-U). In occupational health, workers exposed to toluene are examined for HA-U, because collection of urine samples is easy. The HA-U of some designers in a great household electrical products corporation who did not use toluene occupationally showed relatively high values. Fro...

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Colorimetric determination of hippuric acid in urine and liver homogenate.

To a dried extract Containing hippuric acid (HA), 1.0 mL of acetic anhydride and 2.0 mL of 0.5% p-dlmethyiamlnobenzaldehyde (DAB) solution In pyridine were added, and the solution was kept at 40 O C for 1 h after thorough mlxing. The absorbance was then determlned at 458 nm agalnst a blank containing acetic anhydride, DAB, and pyridine. This method was in good agreement with Beer’s law within 1...

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ژورنال

عنوان ژورنال: J. Chem. Soc., Trans.

سال: 1912

ISSN: 0368-1645

DOI: 10.1039/ct9120101254